Folic acid CAS NO.59-30-3

Folic acid, also known as vitamin B9, offers numerous advantages due to its vital role in various physiological processes. Here are some key benefits:

1. Supports Cell Division and Growth

• DNA Synthesis: Essential for the synthesis and repair of DNA, which is crucial for cell division and growth.
• Cellular Function: Plays a critical role in the production of new cells, making it important for overall health and development.

2. Pregnancy Health

• Prevention of Neural Tube Defects: Significantly reduces the risk of neural tube defects such as spina bifida and anencephaly when taken before and during early pregnancy.
• Supports Fetal Development: Contributes to the proper development of the fetal brain and spinal cord.

3. Red Blood Cell Formation

• Prevention of Anemia: Essential for the production of healthy red blood cells. Deficiency can lead to megaloblastic anemia, where red blood cells are larger than normal and less effective at carrying oxygen.

4. Cardiovascular Health

• Homocysteine Levels: Helps lower levels of homocysteine, an amino acid associated with an increased risk of cardiovascular diseases when present in elevated levels.

5. Mental Health

• Mood Regulation: May contribute to mental well-being and reduce the risk of mood disorders. Deficiency has been linked to symptoms of depression and cognitive decline.

6. Immune System Support

• Immune Function: Plays a role in maintaining a healthy immune system by supporting the production and function of white blood cells.

7. Digestive Health

• Gastrointestinal Function: Supports the health of the gastrointestinal tract, aiding in digestion and nutrient absorption.

8. Versatility

• Supplement Formulation: Available in various forms including tablets, capsules, powders, and fortified foods, making it easy to incorporate into different dietary regimens.
• Fortification: Commonly added to cereals, breads, and other foods to help prevent deficiencies in the general population.

9. General Health and Well-being

• Overall Health: Contributes to overall well-being by supporting numerous bodily functions and processes.
• Reduced Risk of Certain Conditions: Adequate intake is associated with a lower risk of certain health conditions, such as birth defects and some types of anemia.

Summary

Folic acid is a vital nutrient with a wide range of health benefits, from supporting cell growth and division to promoting cardiovascular and mental health. Its importance is particularly emphasized during pregnancy and in the prevention of certain health conditions. The versatility of folic acid in dietary supplements and fortified foods makes it accessible for maintaining overall health and well-being.

Product Details

Product Name: Folic Acid

Chemical Name: (2S)-2-[[(2S)-2-amino-4-hydroxy-6-oxo-1,6-dihydro-pyrimidin-5-yl]methylsulfamoyl]benzoic acid

CAS Number: 59-30-3

Molecular Formula: C19H19N7O6

Molecular Weight: 441.40 g/mol

Appearance:

• Powder: Typically a yellow to orange crystalline powder.
• Solution: Can be in liquid form, generally yellowish.

Solubility:

• Water: Slightly soluble (around 1 g/L).
• Organic Solvents: Soluble in slightly alkaline solutions and some organic solvents.

pH:

• In Solution: Slightly acidic to neutral.

Melting Point: Approximately 250-256°C (482-493°F).

Production

• Synthesis: Folic acid is synthesized through chemical reactions starting from pteridine, para-aminobenzoic acid, and glutamic acid.
• Purification: The raw product is purified to achieve high purity, typically ≥ 95% for most applications.

Applications

1. Nutritional Supplements:

   • Formulations: Available in tablets, capsules, powders, and liquid forms.
   • Use: Commonly used in prenatal vitamins, multivitamins, and B-complex supplements to support overall health and prevent deficiencies.

2. Food Fortification:

   • Fortified Foods: Added to cereals, breads, and other foods to help prevent folic acid deficiency in the general population.

3. Pharmaceuticals:

   • Therapeutic Use: Used in the treatment of folate deficiency and certain types of anemia, such as megaloblastic anemia.

4. Medical Applications:

   • Preventive Health: Often recommended for pregnant women to reduce the risk of neural tube defects in the fetus.

Benefits

• Cell Division and Growth: Supports DNA synthesis and cell division, crucial for tissue growth and repair.
• Pregnancy Health: Reduces the risk of neural tube defects and supports fetal development.
• Red Blood Cell Formation: Helps in the production of healthy red blood cells and prevents anemia.
• Cardiovascular Health: Assists in lowering homocysteine levels, potentially reducing cardiovascular risk.

Safety and Dosage

• Safety Profile: Generally considered safe when used in recommended doses. Excess folic acid is typically excreted in urine.
• Recommended Daily Allowance (RDA):
  • Adults: About 400 micrograms per day.
  • Pregnant Women: About 600 micrograms per day to support fetal development and prevent neural tube defects.

Storage and Handling

• Storage: Store in a cool, dry place away from light and moisture to maintain stability.
• Shelf Life: Typically 2-3 years when stored properly.
• Handling: Use appropriate protective equipment when handling powders to avoid inhalation and prolonged skin contact.

Summary

Folic acid is a crucial B vitamin with significant roles in cell growth, metabolism, and overall health. Its applications span from dietary supplements and food fortification to therapeutic uses in treating deficiencies and supporting pregnancy health. Its versatility and importance in preventing certain health conditions make it a valuable nutrient in both preventive and therapeutic contexts.